Tardive dyskinesia is a movement disorder characterised by irregular, stereotyped, and choreiform movements associated with the use of antipsychotic medication. We aim to provide recommendations on the treatment of tardive dyskinesia. We performed a , This guideline provides evidence-based recommendations for the treatment of tardive syndromes, focusing on effective management strategies and therapeutic interventions., TD, tardive dyskinesia; VMAT2, vesicular monoamine transporter 2. * Level A is the strongest recommendation, established as effective, based on at least 2 consistent class I studies. Level B refers to probably effective treatment, derived from at least 1 class I study or 2 consistent class II studies., Abstract Tardive dyskinesia (TD) is a debilitating, iatrogenic, and potentially severe movement disorder characterized by involuntary, repetitive, purposeless movements that are present throughout the body. The authors present a review of studies of past, current, and possible future treatment approaches to the management of TD; consider the phenomenology, assessment, and putative , TD Treatment The Recommended Treatment Guidelines The 2020 American Psychological Association (APA) Practice Guideline recommends that patients with moderate-to-severe or disabling tardive dyskinesia (TD) be treated with a VMAT2 inhibitor., The American Psychiatric Association updated their practice guidelines for the treatment of schizophrenia in 2020 and recommended “that patients who have moderate to severe or disabling tardive dyskinesia associated with antipsychotic therapy be treated with a reversible inhibitor of the vesicular monoamine transporter 2.” 6.