суть постановления правительства 1137 от 26.12.2011
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суть постановления правительства 1137 от 26.12.2011, Cancer Gene Therapy - Nature, The Current Status of Gene Therapy for the Treatment of Cancer, What is Gene Therapy? - OncoLink, Types of Cancer Treatment - NCI - National Cancer Institute, How is Gene Therapy Being Used to Treat Cancer? - Dana-Farber Cancer , Cancer gene therapy: Understanding the basics - Alliance for Cancer , Gene therapy - Mayo Clinic.
Platelets, traditionally known for their role in hemostasis, are now recognized as key modulators of oncological processes, influencing tumor growth and metastasis through interactions with the tumor microenvironment. Recent studies reveal that platelet activation contributes to T-cell exhaustion by releasing thromboxane A2 (TXA2), which binds to the TBXA2R receptor and activates ARHGEF1, a guanine nucleotide exchange factor (GEF), leading to the suppression of T-cell function. This editorial explores the potential of repurposing anti-platelet drugs, such as aspirin, to counteract these effects. Aspirin, by inhibiting cyclooxygenase enzymes essential for TXA2 synthesis, can enhance T-cell activity in metastatic contexts, thereby improving immune surveillance and response. We advocate for further investigation into the thromboxane pathway’s impact on T-cell functionality and the development of aspirin-based therapeutic strategies to combat cancer metastasis., Cancer Gene Therapy is the essential gene therapy resource for cancer researchers and clinicians, keeping readers up to date with the latest developments in gene therapy for cancer., Gene therapy for cancer treatment has good progress in the last three decades, few drugs approved, while others are still in trials. Relatively gene therapy has better safety with tolerable adverse effects than chemotherapy for the treatment of cancer. In the future, tumor genomic analysis, assessment of host humoral and cellular immunity will .
Stop certain genes that can cause new cancer or the spread of an existing cancer (called “metastasis”). These genes are called “Oncogenes.” By stopping these genes, the cancer and/or its spread may be stopped. Use the body's own immune system by putting genes into cancer cells that trigger the body to attack the cancer cells as foreign , Some people with cancer have only one treatment. But most people have a combination of treatments, such as surgery with chemotherapy and radiation therapy. The types of treatment that you receive will depend on the type of cancer you have and how advanced it is. To learn more about how specific cancers are treated, see the cancer treatment , The first therapeutic cancer vaccine to receive FDA approval is used in the treatment of certain prostate cancer patients. The goal is that the newly inserted gene will cause the cancer cells to die or interrupt some process required for survival, such as preventing cancer cells and surrounding tissue from funneling blood to tumors and , Gene therapy is an element of cancer cell and gene therapy in which researchers alter the DNA and genetic function of immune cells or cancer cells. Researchers are also examining the tumor microenvironment – the environment cancer builds around it to support its growth and block the immune system – of different types of cancers to learn how , Gene therapy aims to fix a faulty gene or replace it with a healthy gene to try to cure disease or make the body better able to fight disease. It holds promise as a treatment for a wide range of diseases, such as cancer, cystic fibrosis, heart disease, diabetes, hemophilia and AIDS., Gene therapy aims to correct the gene to treat the disease by: Adding a new or modified copy of a gene; Turning a gene on or off; Changing a gene, by replacing the part of the gene causing disease with a healthy copy; Types of Gene Therapy. The two main types of gene therapy are gene addition and gene editing..