Nutritional supplements allow us to address different biological pathways that are involved in depressive disorders. In this article, we share the seven supplements for depression that have the most evidence based on research and our clinical experience: Acetyl-L-Carnitine Lithium Rhodiola Chromium B vitamins, including B9 (folate), B6 (P-5-P , WebMD provides information on popular vitamins and supplements including side effects, drug interactions, user ratings and reviews, medication over dose, warnings, and uses., Nutritional deficiencies can sabotage your mood: These vitamins for depression can ease symptoms of anxiety, stress, and other mood-wreckers., Certain vitamins and supplements can offset the effects of depression and anxiety, such as vitamin D, vitamin B, magnesium, and omega-3 fatty acids. Always talk to your doctor and other prescribers before starting a new vitamin or supplement, as many can interact negatively with prescription medications., Low levels of some nutrients can play a part in depression, but should you take vitamins for depression? Learn which vitamins and minerals affect mental health., Thankfully, depression is treatable. The most effective depression treatments are psychotherapy and medication —often a combination of the two. Lifestyle changes that improve your overall health and well-being can also help treat symptoms, including vitamins for depression..