). Serotonin syndrome symptoms may include mental status changes (e.g., confusion, agitation, hallucinations), autonomic instability (e.g., diaphoresis, tachycardia, labile blood pressure, hyperthermia), neuromuscular abnormalities (e.g., tremor, ataxia, hyperreflexia, clonus, muscle rigidity), and/or gastrointestinal symptoms (e.g., nausea, vomiting, diarrhea). Treatment with cyclobenzaprine hydrochloride and any concomitant serotonergic agents should be discontinued immediately if the above reactions occur and supportive symptomatic treatment should be initiated. If concomitant treatment with cyclobenzaprine hydrochloride and other serotonergic drugs is clinically warranted, careful observation is advised, particularly during treatment initiation or dose increases (see , Pill with imprint 022 is Orange, Round and has been identified as Cyclobenzaprine Hydrochloride 10 mg. It is supplied by TruPharma LLC. Cyclobenzaprine is used in the treatment of Muscle Spasm; Back Pain; Sciatica; Pain and belongs to the drug class skeletal muscle relaxants. There is no proven risk in humans during pregnancy., The 022 Orange Round Pill is commonly used to treat muscle spasms and pain caused by injuries or other conditions. The recommended dosage for adults is 10 mg, taken thrice daily..