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Chloride Blood Test: What It Is, Purpose, Procedure & ResultsLocations:||||||Home/Health Library/Diagnostics & Testing/Chloride Blood TestAdvertisementAdvertisementChloride Blood TestChloride is one of the electrolytes in your blood. Chloride blood tests check to make sure you have appropriate levels of chloride in your blood to be healthy. Many factors can cause an abnormal level of chloride in your blood, including dehydration, vomiting and certain medical conditions.AdvertisementCleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. PolicyCare at Cleveland ClinicFind a Primary Care ProviderSchedule an AppointmentContentsArrow DownContentsArrow DownOverviewA chloride blood test requires a blood sample, usually taken from a vein in your arm.What is a chloride blood test?A chloride blood test (serum chloride) measures the level of chloride in your blood.AdvertisementCleveland Clinic is a non-profit academic medical center. Advertising on our site helps support our mission. We do not endorse non-Cleveland Clinic products or services. PolicyChloride is an electrolyte. Electrolytes are minerals that carry an electric charge when they’re dissolved in a liquid. The electrolytes in your blood — chloride, sodium, potassium and bicarbonate — help control nerve and muscle function and maintain the acid-base balance (pH balance) of your blood and your water balance.The amount of chloride in your blood is often measured along with other electrolytes to diagnose or monitor certain medical conditions, including:Kidney disease.Heart failure.Liver disease.High blood pressure.What is a chloride blood test used for?Healthcare providers usually don’t order individual chloride blood tests. Chloride blood tests are usually included in the following routine blood tests and screenings that measure multiple things in your blood:Comprehensive metabolic panel (CMP).Basic metabolic panel (BMP).Electrolyte panel.Renal function panel (RFP).Why do I need a chloride blood test?Your healthcare provider may order a chloride blood test as part of a routine blood panel. They can also order a chloride blood test if you have symptoms of an acid or fluid imbalance, including:Experiencing multiple instances of vomiting.Having diarrhea.Feeling very tired (fatigue).Feeling weak.Experiencing dehydration.Having difficulty breathing.AdvertisementTest DetailsWhat does a chloride blood test tell you?The results of a chloride blood test, alongside the results of other electrolyte tests, can help diagnose a condition related to an imbalance of acids or fluids in your body.How do I prepare for my chloride blood test?You don’t need any special preparations for a chloride blood test or an electrolyte panel.A chloride blood test may be part of a basic or comprehensive metabolic panel, which measures multiple things in your blood. In this case, you may need to not eat or drink (fast) for several hours before your blood draw. Your healthcare provider will let you know if you need to follow any special instructions.What should I expect during my chloride blood test?You can expect the following during a blood test:A healthcare provider (usually a phlebotomist) will check your arms for an easily accessible vein. This is usually in the inner part of your arm on the other side of your elbow.Once they’ve located a vein, they’ll clean and disinfect the area.They’ll then insert a small needle into your vein to take a blood sample. This may feel like a tiny pinch.After they insert the needle, a small amount of blood will collect in a test tube.Once they have enough blood to test, they’ll remove the needle and hold a cotton ball or gauze on the site to stop the bleeding.They’ll place a bandage over the site, and you’ll be finished.What should I expect after my chloride blood test?After a healthcare provider has collected your blood sample, they’ll send it to a laboratory for testing. Once the test results are back, your healthcare provider will share the results with you.Care at Cleveland ClinicFind a Primary Care ProviderSchedule an AppointmentResults and Follow-UpHaving too much or too little chloride in your blood could be a sign of a health condition.What type of results do you get for a chloride blood test?Blood test reports, including chloride blood test reports, usually provide the following information:The name of the blood test or what was measured in your blood.The number or measurement of your blood test result.The normal measurement range for that test.Information that indicates if your result is normal or abnormal or high or low.What is a normal chloride blood test result?A typical normal range for a chloride blood test for an adult is 96 to 106 milliequivalents per liter (mEq/L) or 96 to 106 millimoles per liter (mmol/L). But laboratories may have different reference ranges for normal chloride levels. When you get your blood test results back, there will be information that indicates what that lab’s normal blood chloride range is. If you have any questions about your results, be sure to ask your healthcare provider.What does a low chloride level mean?If your results reveal that you have lower-than-normal levels of chloride in your blood, it may indicate that you have:Heart failure.Lung diseases, like emphysema.Addison’s disease.Metabolic alkalosis.It’s important to remember that a low chloride result doesn’t necessarily mean that you have a medical condition. Certain situations and medications can also increase your chloride levels.AdvertisementWhat does a high chloride level mean?If your results reveal that you have higher-than-normal levels of chloride in your blood, it may indicate that you have:Dehydration.Kidney disease.Cushing’s syndrome.Metabolic acidosis.Respiratory alkalosis.It’s important to remember that a high chloride result doesn’t necessarily mean that you have a medical condition. Certain situations and medications can also increase your chloride levels.Should I be concerned if I have a low or high chloride blood test result?If your chloride blood test results reveal that you have high or low levels of chloride, it doesn’t necessarily mean that you have a medical condition. Many factors can affect your chloride levels, including:Drinking excess fluids.Losing fluids due to vomiting or diarrhea.Certain medicines, like antacids.An error in the blood test collection.Your healthcare provider will interpret your chloride result within the context of certain factors, like other test results and your medical history. If you have questions about your results, be sure to ask your healthcare provider for more information.When should I know the results of my chloride blood test?In most cases you should have your chloride blood test results within two business days.A note from Cleveland ClinicReceiving an abnormal test result can be stressful. Know that having a high or low level of chloride in your blood doesn’t necessarily mean you have a medical condition and need treatment, though. Many other factors can affect your chloride levels. Your healthcare provider will let you know if you need further tests to determine the cause of the abnormal level. Don’t be afraid to ask your healthcare provider questions. They’re there to help you.AdvertisementCare at Cleveland ClinicCleveland Clinic’s primary care providers offer lifelong medical care. From sinus infections and high blood pressure to preventive screening, we’re here for you.Find a Primary Care ProviderSchedule an AppointmentMedically ReviewedLast reviewed on 10/28/2024.Learn more about the and our .ReferencesAdvertisementAdvertisementAdLab Appointments & LocationsRendered: Sat Aug 16 2025 17:30:30 GMT+0000 (Coordinated Universal Time)ActionsBlog, News & AppsAbout Cleveland ClinicSite Information & Policies9500 Euclid Avenue, Cleveland, Ohio 44195 | 800.223.2273 | © 2025 Cleveland Clinic. All Rights Reserved., Chloride is one of the electrolytes in your blood. Chloride blood tests check to make sure you have appropriate levels of chloride in your blood to be healthy. Many factors can cause an abnormal level of chloride in your blood, including dehydration, vomiting and certain medical conditions., Normal chloride levels for adults are in the 96–106 mEq/L range. If your test shows a chloride level higher than 106 mEq/L, you have hyperchloremia. Normal ranges may sometimes differ by lab..
Maintaining chloride levels in your blood is critical to health. Learn more about how chloride levels in your blood are determined and what the results mean., What High Chloride Levels Indicate Elevated chloride levels in the blood, known as hyperchloremia, can signal various underlying issues. This imbalance often occurs alongside other electrolyte disturbances. Severe dehydration is a common cause, where the body loses more fluid than electrolytes, leading to a higher chloride concentration., Chloride is an electrolyte in your blood that helps keep you hydrated. A chloride blood test measures this electrolyte and tells you if your levels are high or low., Chloride in your blood is very essential in keeping the proper balance of the fluid and acid in your body. It also helps in maintaining your blood pressure, blood volume, and pH levels. The chloride blood test, or serum chloride level, is used to measure the chloride levels in your blood., Learn about serum chloride, its role in electrolyte balance, normal levels, and what abnormal results mean for your health. Understand symptoms, causes, and treatments., Many diseases and other factors can cause abnormal chloride levels. Chloride is often measured with other electrolytes to diagnose or monitor conditions such as kidney disease, heart failure, liver disease, and high blood pressure..