Approved in 2007 for Crohn's diseaseApproved for use in children ages 6 and upAlso approved for rheumatoid arthritis, plaque psoriasis, psoriatic arthritis, and ankylosing spondylitisTwo biosimilars are available: Cyltezo (Adalimumab-adbm) and Amjevita (Adalimumab-atto)Given as a shot under the skin using an auto-injector penFirst injection is four times the normal dose, the second dose is two times a normal dose, then one injection is needed every two weeksCost is about $2,900 per pen, Biologics are drugs made from living cells, and they can be a viable treatment for Crohn's disease. Learn more about which biologic drugs are available to treat Crohn's disease at WebMD., Biologics are first-choice treatment options for moderate-to-severe Crohn’s disease. Nine biologics are currently FDA approved to treat it. Humira (adalimumab), Remicade (infliximab), and Stelara (ustekinumab) are a few examples of biologics that manage moderate-to-severe Crohn’s disease..