Types of Drug Treatment Options for Migraine Prevention. Your doctor will work with you to create a migraine prevention plan based on your specific needs. This means taking into account any other conditions for which you are currently taking medication and/or which may be impacted by certain preventive migraine treatments., Migraine prevention injection is one of many treatment options for migraine, a type of recurring headache. Migraine headaches may cause intense pulsing or throbbing pain, often on one side of the head. Four injectable prescription medications are available to prevent migraines in adults: Aimovig, Vyepti, Ajovy, and Emgality., Botulinum toxin type A, commonly referred to as Botox, was approved by the Food and Drug Administration (FDA) as a preventative migraine treatment in 2010. Individuals who have migraine headaches more than 15 days per month may be candidates. Botox is administered in a doctor’s office., , , .