Persistent or severe symptoms warrant seeking guidance from a healthcare professional. They may prescribe medications, like PPIs, if your symptoms don't improve. For short-term relief, taking acid reflux medications daily is generally safe for a few weeks at a time. For example, you can take PPIs or histamine antagonists daily for up to two weeks., All of these over-the-counter medicines, to a varying degree, can relieve the symptoms of heartburn. If you have more severe heartburn symptoms that these medications don't relieve, or if you've , Get heartburn relief fast with top products from CVS. Browse our selection of heartburn medicine and get FREE shipping on most orders., Heartburn medicine factors to consider. When shopping for a new heartburn medicine, there are a number of important factors to consider. Some consumers might only need short-term relief from occasionally eating trigger foods. Others might need a longer-term treatment for chronic acid reflux, GERD, or a sensitive stomach., TREATS FREQUENT HEARTBURN: Heartburn medicine for those who experience heartburn flare ups 2+ times a week ; With 1 PRILOSEC OTC PILL EACH MORNING, 24 HOURS. ZERO HEARTBURN.* Unlike antacids which last only 1-3 hours ; PREVENT EXCESS ACID PRODUCTION for heartburn relief that lasts for 24 HOURS.* Starts working on DAY 1*, Figuring out what your situation calls for and then choosing a medication based on that will help you land the right choice. Consider these three factors to determine which option would be the best heartburn medicine for you. Quick Acting or Delayed Release. Heartburn medication comes in two major forms – quick acting or delayed release. If .