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фурагин инструкция по применению для детей суспензия

фурагин инструкция по применению для детей суспензия

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фурагин инструкция по применению для детей суспензия, Фурагин — инструкция по применению, дозы, побочные действия , Фурагин инструкция по применению: показания, противопоказания , Фурагин: инструкция по применению, аналоги, состав, показания, ФУРАГИН таблетки - инструкция по применению, цена, дозировки , Фурагин - официальная инструкция по применению, аналоги, цена , Фурагин: инструкция по применению, отзывы и цены, Фурагин (Furagin): описание, рецепт, инструкция.
ФармакодинамикаФуразидин — противомикробное средство широкого спектра действия. Резистентность к фуразидину развивается медленно и не достигает высокой степени. Активен в отношении грамположительных Staphylococcus spp. (Staphylococcus aureus, Staphylococcus saprophyticus, Staphylococcus epidermidis), Streptococcus spp. и грамотрицательных Escherichia coli, Salmonella spp., Shigella spp., Klebsiella spp., Enterobacter spp. микроорганизмов. Устойчивы к фуразидину Pseudomonas aeruginosa, Enterococcus spp., Acinetobacter spp., большинство штаммов Proteus spp., Serratia spp. В отношении большинства бактерий бактериостатическая концентрация составляет от 10 до 20 мкг/мл. Бактерицидная концентрация примерно в 2 раза выше. Нитрофураны подавляют активность дыхательной цепи и цикл трикарбоновых кислот (цикла Кребса), а также угнетают другие биохимические процессы, что приводит к разрушению оболочки или цитоплазматической мембраны микроорганизмов.Множественный механизм действия объясняет слабую приобретенную устойчивость микроорганизмов к нитрофуранам. В результате действия нитрофуранов микроорганизмы выделяют меньше токсинов, в связи с чем улучшение общего состояния пациента возможно еще до выраженного подавления роста микроорганизмов.ФармакокинетикаАбсорбция происходит в тонкой кишке путем пассивной диффузии. Всасывание нитрофуранов из дистального сегмента тонкой кишки превышает всасывание из проксимального и медиального сегмента в 2 и 4 раза соответственно (следует учитывать при одновременном лечении урогенитальных инфекций и заболеваний ЖКТ, в т.ч. с хроническим энтеритом). Плохо всасывается в толстой кишке.Распределяется равномерно. В высоких концентрациях содержится в лимфе, в желчи его концентрация в несколько раз выше, чем в сыворотке, в ликворе — в несколько раз ниже, чем в плазме, в слюне содержится до 30% от его концентрации в плазме, в крови и тканях концентрация небольшая, что связано с быстрым выведением, при этом концентрация в моче значительно выше, чем в крови. Cmax в плазме крови сохраняется от 3 до 7–8 ч, в моче обнаруживается через 3–4 ч. Не изменяется pH мочи в отличие от действия нитрофурантоина.Метаболизируется в печени (менее 10%), при снижении выделительной функции почек интенсивность метаболизма возрастает.Выводится почками путем КФ и канальцевой секреции (85%), частично подвергается обратной реабсорбции в канальцах. При низких концентрациях в моче преобладает процесс фильтрации и секреции, при высоких — уменьшается секреция и увеличивается реабсорбция. Являясь слабой кислотой, не диссоциирует, при кислых значениях pH мочи подвергается интенсивной реабсорбции, что может усилить системное побочное действие., Фурагин: инструкция, показания и противопоказания, цены и заказ в аптеках, способ применения и дозы, побочные действия, взаимодействие в Энциклопедии лекарств РЛС., Показания препарата Фурагин лечение инфекционно-воспалительных заболеваний мочевыводящих путей; лечение вторичных инфекционных осложнений после оперативных вмешательств на органах .
Фурагин - антибактериальное средство с бактериостатическим действием, эффективно как в отношении грамположительных (Staphylococcus epidermidis, Staphylococcus aureus, Staphylococcus faecalis), так и грамотрицательных , Инструкция по применению препарата ФУРАГИН таблетки: дозировки, побочные эффекты, противопоказания, аналоги, условия отпуска из аптек., Фурагин принимают внутрь, после еды – по 50-100 мг 3 раза в сутки в течение 7-10 дней., Фурагин – медицинский препарат из группы нитрофуранов – противомикробное и антибактериальное средство, эффективно воздействующее на стафилококки, стрептококки и многие другие виды , Справочник лекарственных препаратов. Полное описание, рецепты, фармакология и инструкция по применению., Фурагин инструкция по применению препарата ⭐️ Показания и противопоказания.
 
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