The Fred Hutchinson Cancer Research Center/University of Washington often enrolls patients with MDS-EB2 in trials of newly diagnosed AML, 46 as does MD Anderson Cancer Center, 58 which found little evidence that marrow blast percentage considered as 10% to 19%, 20% to 29%, or ≥30% had independent effects on survival in patients age <60, 60 to , Now MDS is considered a form of cancer. MDS can also develop into a more serious cancer. In about 1 in 3 people with MDS, the disease can progress to acute myeloid leukemia (AML) , a fast-growing cancer of bone marrow cells., The Myelodysplastic Syndromes (MDS) and Acute Myeloid Leukemia (AML) are a heterogeneous group of malignant clonal hematopoietic stem cell disorders. MDS is characterized by ineffective hematopoiesis, marrow dysplasia, peripheral blood cytopenia, and a high propensity for transformation into AML., , , .