IH is a 24-hour condition with multiple symptoms including excessive daytime sleepiness, sleep inertia (severe grogginess or confusion when waking up), cognitive impairment (brain fog), long sleep time, and unrefreshing sleep. XYWAV is the first and only FDA-approved medication to treat IH in adults. XYWAV has been studied across multiple , XYWAV ® (calcium, magnesium, potassium, and sodium oxybates) oral solution, 0.5 g/mL total salts (equivalent to 0.413 g/mL of oxybate) is indicated for the treatment of cataplexy or excessive daytime sleepiness (EDS) in patients 7 years of age and older with narcolepsy, and for the treatment of idiopathic hypersomnia (IH) in adults., Excessive Daytime Sleepiness (EDS) with Narcolepsy. 1-3 . Authorization of 12 months may be granted for continued treatment of excessive daytime sleepiness (EDS) with narcolepsy when the member has demonstrated beneficial response to treatment as defined by a decrease in daytime sleepiness with narcolepsy from baseline. Idiopathic hypersomnia. 1,5, Calcium, magnesium, potassium, and sodium oxybates oral solution: A lower-sodium alternative for cataplexy or excessive daytime sleepiness associated with narcolepsy. Nature and Science of Sleep. Heo, Y.-A. (2022). Calcium, magnesium, potassium and sodium oxybates (Xywav) in sleep disorders: A profile of its use. CNS Drugs. Hypersomnia , Medications available for idiopathic hypersomnia (IH) include both FDA-approved and off-label options: FDA-Approved Medication: Xywav (calcium, magnesium, potassium, and sodium oxybates): This is the first and only FDA-approved treatment specifically for idiopathic hypersomnia in adults.It is a lower-sodium oxybate formulation taken at night to treat symptoms such as excessive daytime , Idiopathic hypersomnia is a debilitating neurologic sleep disorder characterized by chronic excessive daytime sleepiness, making it difficult to stay awake and alert during the day. Xywav (calcium, magnesium, potassium, and sodium oxybates) is the first and only FDA-approved treatment for idiopathic hypersomnia. Drugs.com Mobile App .