Learn about the side effects of Shingrix (zoster vaccine, recombinant), from common to rare, for consumers and healthcare professionals., The shingles vaccine called Shingrix helps your body create a strong defense against shingles. As a result, you are likely to have temporary side effects from getting the shots. Two doses of Shingrix provides more than 90% protection against shingles and its complications., Shingles is a viral infection caused by the chickenpox virus. It can cause an itchy, painful rash. Some people experience burning pain at their rash site for months or even years after the, Some people have a reaction to the vaccine, typically ranging from soreness at the injection site to feeling a little under the weather for a few days. The Shingrix vaccine reduces the risk of developing shingles (herpes zoster)., Serious side effects are rare, but not impossible, after shingles vaccination. If you develop hives, swelling of the face or throat, difficulty breathing, a rapid heartbeat, or sudden dizziness or weakness, call 911 and seek medical care immediately., Shingrix is generally well tolerated. Still, you may have side effects such as arm pain, headache, or fever for a couple of days after receiving the vaccine. Take it easy and avoid heavy physical activity after your shingles vaccine shot..