Many medications claim to relieve migraine pain, but some are more helpful than others. In a large study looking at real-world data on 25 drugs, migraine sufferers rated the most and least helpful options., From prescription medications to better sleep, finding the right migraine treatments can be hard. Learn the stages of a migraine and the best options for relief., Antimigraine agents are used to treat migraine headaches. Migraines are different from other headaches because they occur with symptoms such as nausea, vomiting, or sensitivity to light. Some people who get migraines have warning symptoms, called an aura, before the actual headache begins. Pain relieving drugs can be taken as soon as the pain begins and include agents in the drug classes such , , , .