Cranial nerve IV (trochlear nerve) is a somatic motor nerve that innervates the superior oblique muscle, which intorts, infraducts, and abducts the globe. The nucleus of CN IV lies at the level of the inferior colliculus in the tegmentum of the midbrain., This patient highlights all of the typical features of bilateral 4th nerve palsies, including a V-pattern esotropia, reversing hypertropia on left and right gaze (also with left and right head tilt - not shown), underaction of the superior oblique in depression while adducting, and overaction of the inferior oblique in elevation while adducting. There was also 15 degrees of excyclotorsion , The most widely accepted etiology of trochlear pain is inflammatory. First documented in 1984, biopsy of the superior oblique muscle in a patient with trochlear pain showed perivascular lymphocytic invasion of the myofibrils [15]., Mikami T, Minamida Y, Ohtsuka K, Houkin K. Resolution of superior oblique myokymia following microvascular decompression of trochlear nerve. Acta Neurochir (Wien) 2005;147 (9):1005-1006., The clinical presentation typically consists of various combinations of ocular motor nerve impairments (Oculomotor Nerve - CN III, Trochlear Nerve - CN IV, and Abducens Nerve - CN VI), Horner syndrome, and sensory loss of the first (V1) or second (V2) division of the trigeminal nerve (CN V). There are a variety of etiologies that can cause this., Heather A. Stiff, MD Dr. Heather Stiff is an ophthalmologist at Children's Hospital and Medical College of Wisconsin in Milwaukee, WI. Dr. Stiff completed her Ophthalmology Residency at the University of Iowa Department of Ophthalmology and Visual Sciences in June 2020, continuing on to complete a Pediatric Ophthalmology and Strabismus Fellowship at the University of Iowa Department of .