Tardive dyskinesia is primarily linked to the long-term use of medications that block dopamine receptors in the brain. Antipsychotic drugs, particularly older first-generation antipsychotics, are the most common cause because they interfere with dopamine signaling, a neurotransmitter crucial for movement regulation., People with schizophrenia who take medication may develop a condition called tardive dyskinesia (TD), but what is TD, and why does it happen?, Individuals with tardive dyskinesia, as with any individual with schizophrenia, should be treated in the context of a person-centered treatment plan that includes evidence-based non-pharmacological and pharmacological treatments. Tardive syndromes can occur after exposure to any antipsychotic medication., , , .