Summary: Start from the corner and measure out 16” to the center of the first stud, then continue at 16” on center. That way you’ll use a full sheet of sheathing at the corner. Often contractors will measure out only 15 1/2” so the siding laps good at the corner too and covers the sheathing., Bob Schmidt shows you how and why to lay-out a wall during construction to a standard 16 inch on center lay-out., In construction, 16 O.C. stands for 16 inches on center, a measurement used to specify the spacing between framing members such as wall studs, floor joists, ceiling joists, and rafters., In this video, I show you a very basic way to at least get you started and understanding how to frame a wall. Now either with 2×4’s or 2×6’s, it’s all done the same way. You’ll have a top plate and a bottom plate that the uprights (studs) will go between every 16 inches., If you’ve reached the point in your DIY house building project where you need to build a wall with a door opening, this article will teach you how to do just that. As usual, I’ll be basing my framework measurements on the most common layout, which is 16 inches on center. Be sure to ALWAYS, 16 inch on center, or 16″ o.c., means that from the center of one stud to the center of the next stud is approximately 16 inches. Wall studs , floor joists and rafters are spaced this way to accommodate 4X8 foot sheets of plywood, drywall or paneling..