Learn about cost, uses, and more for Kymriah (tisagenlecleucel), which is a prescription infusion that treats certain types of cancer., The bottom line Kymriah (tisagenlecleucel) is a CAR T-cell therapy medication. It uses your own immune system to fight leukemia and lymphoma. However, Kymriah can cause side effects, some of which can be life-threatening and require hospitalization. To determine if Kymriah is a treatment option for you, it’s recommended to speak with your cancer specialist., What is Kymriah™ (tisagenlecleucel)? Kymriah is an FDA-approved immunotherapy — a treatment designed to help your own immune system fight cancer. Specifically, it is a type of chimeric antigen receptor (CAR) T-cell therapy., General Info Kymriah is a c himeric antigen receptor T-cell, or CAR-T, therapy. A patient’s T cells are collected, genetically reprogrammed by inserting an artificial receptor, multiplied in a lab and reinfused into the same individual. These synthetic receptors help the engineered T cells recognize and attack cancer cells. Specifically, Kymriah targets the CD19 protein on B cells that grow , Kymriah is a brand-name prescription cell therapy. It’s FDA-approved to treat certain types of relapsed* or refractory* cancer. Specifically, Kymriah can be used in: Children and young adults , Kymriah, the first FDA-approved CAR T-cell therapy, has significantly transformed cancer treatment, particularly for blood cancers like pediatric acute lymphoblastic leukemia (ALL) and adult diffuse large B-cell lymphoma (DLBCL). This innovative therapy involves collecting and genetically modifying a patient’s T cells to target CD19, a protein on B cells, resulting in complete remission .