Hemlibra® works by replacing the function of factor VIII, rather than replacing the missing clotting factor VIII directly. It can be used to either prevent or reduce the frequency of bleeding episodes in people with hemophilia A. This treatment product can be given by injection under the skin. Patients who use Hemlibra® for prophylaxis and use clotting factor concentrates to treat breakthrough bleeds can still develop an . Traditional laboratory inhibitor testing methods do not work when testing for inhibitors in patients on Hemlibra®; as such, a specialized testing method called the chromogenic Bethesda assay is needed., For hemophilia A, another treatment method is a non-factor product that stands in for, or replaces the function of, the missing factor VIII. This treatment is given by injection under the skin that can be given by people with hemophilia themselves. Healthcare providers typically prescribe treatment products for episodic care or prophylactic care., Dr. Sridharan recommends working with a hemophilia treatment center to guide treatment and care. You can find and contact regional hemophilia treatment centers through the CDC’s online directory. Understanding your treatment options. There are three main types of hemophilia treatment: factor replacement, non-factor replacement and gene therapy..