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торговый дом лебединский в ростове официальный сайт, FDA Greenlights New Treatment for Advanced Blood Cancer - WebMD, Multiple Myeloma: Improved Prognosis With the Latest Treatments, Linvoseltamab Approved for R/R Multiple Myeloma - Medscape, Darzalex Faspro, Sarclisa Approvals for Multiple Myeloma, FDA Approves Regeneron Multiple Myeloma Drug With Dosing Edge Over J&J , Cancer Care Northwest offers blood cancer treatment alternative, FDA Approves Linvoseltamab to Treat R/R Multiple Myeloma.
Conditions Back ConditionsDrugs & Supplements Back Drugs & SupplementsWell-Being Back Well-BeingMore Back More Privacy & More Subscribe Log In Search Subscribe GuideOverviewCauses & RisksSymptomsDiagnosis & TestsTypesTreatment Living WithComplicationsAppointment Prep View Full Guide FDA Greenlights New Treatment for Advanced Blood CancerWritten by Joyani Das3 min readJuly 3, 2025 — A new treatment has received a quick federal nod for a common blood cancer, which could affect more than 36,000 people and result in around 12,000 deaths in the U.S. this year alone. The drug, known as linvoseltamab but sold under the name Lynozyfic, is for adults with whose cancer has returned or isn't responding well to treatment, especially if they’ve already tried at least four other treatments. Lynozyfic is said to offer a flexible dosing plan tailored to each patient's needs.In multiple myeloma, plasma cells (a type of white blood cell that makes antibodies against diseases) multiply abnormally, leading to too much of a protein called immunoglobulin in bones and blood that crowds out healthy blood cells in the bone marrow. This damages the bones and eventually multiple organs as the disease worsens and spreads. B-cell maturation antigen (BCMA) is a protein found in high levels on multiple myeloma cells that promotes their survival and growth, making the cancer more aggressive and difficult to treat. Despite undergoing three to four therapies, many patients see their cancer return, highlighting the need for new treatments, especially those targeting BCMA. Lynozyfic was approved after a study with 80 people who had multiple myeloma and had already tried at least four other treatments. About 70% of them got better with Lynozyfic. Of those people, about 9 out of 10 were still doing well after nine months, and about 7 out of 10 were still doing well after a year. Scientists watched the patients for about 13 months. About 45% of patients receiving Lynozyfic had no measurable sign of cancer after treatment, according to a from Regeneron Pharmaceuticals, the drug’s maker.“The FDA approval of Lynozyfic is a welcome milestone. It provides appropriate multiple myeloma patients and their care teams with a novel patient-centric treatment option that includes a dosing schedule that can be adapted based on patient response,” said Diane Moran, interim CEO and senior vice president of strategic planning at the International Myeloma Foundation. Lynozyfic works by connecting special immune cells called T cells to cancer cells in the blood (multiple myeloma cells). This helps the T cells find and kill the cancer cells that usually hide from the immune system. Lynozyfic can be given quickly. It could be an option for people who can’t get a similar but stronger treatment called CAR T therapy, which is harder to make and can have serious side effects. Lynozyfic is given through a drip into your vein. At first, people get three small doses that get bigger each time: 5 milligrams, 25 milligrams, and then 200 milligrams. After that, they get 200 milligrams once a week for 10 weeks, then once every two weeks. If they’re doing well at week 24 and have had at least 17 doses, they can switch to once every four weeks.The most common side effects are bone or muscle pain, feeling tired, headache, cough, shortness of breath, weakness, diarrhea, and feeling sick to your stomach.Some serious side effects can happen, like a very strong immune reaction, problems from the infusion, or nerve damage. Because of these risks, patients may need to stay in the hospital for 24 hours after their first two doses. Lynozyfic is only given through a special safety program to help keep people safe.Other warnings include a higher chance of infections, low blood cell counts, liver problems, and harm to fetuses. People need to use birth control during treatment and for three months after their last dose. Patients should not drive, use heavy machines, or do dangerous activities for 48 hours after each first dose or if they have new nerve problems like confusion, shaking, or numbness until they feel better.SourcesShareSOURCES:FDA: “FDA grants accelerated approval to linvoseltamab-gcpt for relapsed or refractory multiple myeloma.”Regeneron Pharmaceuticals: “Lynozyfic™ (linvoseltamab-gcpt) Receives FDA Accelerated Approval for Treatment of Relapsed or Refractory Multiple Myeloma.”Journal of Clinical Oncology: “Linvoseltamab for Treatment of Relapsed/Refractory Multiple Myeloma.”ShareMore on Multiple Myeloma Recommended FEATURED Top doctors in , Find more top doctors on Search Related LinksPoliciesAboutFor Advertisers © 2005 - 2025 WebMD LLC, an company. All rights reserved. WebMD does not provide medical advice, diagnosis or treatment. , In multiple myeloma, plasma cells (a type of white blood cell that makes antibodies against diseases) multiply abnormally, leading to too much of a protein called immunoglobulin in bones and blood , Learn how multiple myeloma prognosis has improved significantly with the emergence of new drug treatments..
Given the advantages over its rivals, Regeneron is hopeful its bispecific antibody will become the new standard of care for relapsed/refractory multiple myeloma., FDA recently approved Darzalex Faspro and Sarclisa combined with standard treatment regimens for people with newly diagnosed multiple myeloma., Bispecific antibodies are already available for treating multiple myeloma. FDA approval of Regeneron Pharmaceuticals’ new drug, Lynozyfic, comes with dosing flexibility that sets it apart from , The Spokane medical community is emerging as a national leader in a new treatment for multiple myeloma, a serious form of blood cancer, says Dr. Hakan Kaya, an oncologist, hematologist, and senior partner at Spokane-based Cancer Care Northwest. An alternative to chemotherapy, referred to as , References Lynozyfic (linvoseltamab-gcpt) receives FDA accelerated approval for treatment of relapsed or refractory multiple myeloma. Regeneron. News release. July 2, 2025., Also, read these articles: Hope, time and new options after CAR-T cell therapy for multiple myeloma Multiple myeloma: Its evolution, treatment and the quest to catch it early No place like home: David Elder’s post-transplant care a ‘blessing’ A version of this article was originally published on the Mayo Clinic News Network..