A wide range of nutritional supplements have been purported to relieve joint pain and inflammation. 7. Fish oil. The polyunsaturated omega-3 fatty acids found in fish have potent anti-inflammatory properties. Research has shown that in people with RA omega-3 supplements reduced joint pain, stiffness and swelling. 8. SAM-e., Pain medicines that you can buy without a prescription can help ease occasional pain triggered by activity your muscles and joints aren't used to, such as gardening after a winter indoors. These medicines include acetaminophen (Tylenol, others), ibuprofen (Advil, Motrin IB, others) and naproxen sodium (Aleve)., Symptoms can differ depending on which joint is affected. Knee joints: moving the knee causes a grating or scraping sensation; Hip joints: Pain may radiate down the inside of the knee or thigh or be felt in the groin or buttock area; Fingers: Bony growths (spurs) may occur inside the joint causing the joints to become swollen, tender and red, Non-opioid pain relievers such as NSAIDs, acetaminophen, anti-seizure drugs, and antidepressants work better for joint pain. Opioids should only be a last resort when no other treatment has helped., Joint pain refers to discomfort, aches, and soreness in any of the body’s joints. It may help to use topical pain relievers or take nonsteroidal anti-inflammatory drugs to reduce pain , Joint pain treatment includes: Simple at-home remedies: Your healthcare provider may recommend applying a heating pad or ice onto the affected area for short periods, several times a day. Soaking in a warm bathtub may also offer relief. Exercise: Exercise can help get back strength and function. Walking, swimming or another low-impact aerobic .