Persistent or severe symptoms warrant seeking guidance from a healthcare professional. They may prescribe medications, like PPIs, if your symptoms don't improve. For short-term relief, taking acid reflux medications daily is generally safe for a few weeks at a time. For example, you can take PPIs or histamine antagonists daily for up to two weeks., All of these over-the-counter medicines, to a varying degree, can relieve the symptoms of heartburn. If you have more severe heartburn symptoms that these medications don't relieve, or if you've , Get heartburn relief fast with top products from CVS. Browse our selection of heartburn medicine and get FREE shipping on most orders., 50-count of Maximum Strength Pepcid AC All-Day Heartburn Relief Tablets with famotidine, for the prevention and relief of heartburn due to acid indigestion and sour stomach Just 1 tablet of the extra strength heartburn medicine controls acid all day or all night (based on 9-hour acid control studies during the day and 12-hour acid control , Over-the-counter (OTC) medications, such as antacids and H2 blockers, can help treat heartburn. People can also try home remedies, including ginger and apple cider vinegar. If symptoms persist, a , Heartburn medicine factors to consider. When shopping for a new heartburn medicine, there are a number of important factors to consider. Some consumers might only need short-term relief from occasionally eating trigger foods. Others might need a longer-term treatment for chronic acid reflux, GERD, or a sensitive stomach..