Xtandi is a prescription drug used to treat prostate cancer in adults. Learn about side effects of the drug and how to manage them. Xtandi is approved to treat prostate cancer in males.* It , Learn about the side effects of Xtandi (enzalutamide), from common to rare, for consumers and healthcare professionals. Zytiga (abiraterone) is used together with prednisone to treat prostate cancer that has spread to Reviews & ratings. 8.2 / 10. 41 Reviews. Availability Prescription only Rx. Pregnancy & Lactation Risk data , Enzalutamide is a medication used to treat prostate cancer in adult males. Common side effects of enzalutamide include fatigue, weakness, decrease in hemoglobin level, decrease in count of neutrophil immune cells, decrease in white blood cell count, high blood glucose level (hyperglycemia), electrolyte disturbances, back pain, joint pain (arthralgia), musculoskeletal pain, muscular weakness , To learn more about Xtandi’s side effects, view the drug’s prescribing information. Call your doctor right away if you have serious side effects with Xtandi. However, if you think you’re having a medical emergency or have life threatening side effects, call 911 or a local emergency number. Serious side effects of Xtandi and their possible , Enzalutamide (Xtandi®) is a drug that is used to treat people with prostate cancer. It is also called antiandrogen or a nonsteroidal antiandrogen (NSAA). 1. Enzalutamide is for people with: 1-4. Castration-resistant prostate cancer (CRPC) Metastatic prostate cancer (cancer that has spread to other areas of the body), Non-metastatic castration-resistant prostate cancer (nmCRPC) Metastatic castration-resistant prostate cancer (mCRPC). (in combination with hormone therapy and docetaxel) and nmCRPC; Enzalutamide (Xtandi®) is approved for high-risk biochemical recurrence, mHSPC, nmCRPC, and mCRPC; including side effects and interactions with other .