Today, the U.S. Food and Drug Administration approved a novel treatment for hemophilia A or B, with or without factor VIII or IX inhibitors (neutralizing antibodies)., Recombinant antihemophilic factor, porcine sequence. Historically, porcine factor VIII has provided a good effect. A porcine sequence recombinant FVIII (rpFVIII; Obizur) was approved by the US Food and Drug Administration (FDA) in 2014 for treatment of bleeding episodes in adults with acquired hemophilia., By educating patients on their factor VIII activity and different treatment options, healthcare providers can set individualized and achievable goals. This collaborative approach may enhance adherence to treatment, reduce bleeding episodes, and improve overall quality of life., The improvements are based on the development of activated recombinant factor VII (in 1996) and factor IX (in 1997), the introduction of immune tolerance programmes (in 1994), the availability of newer treatment options such as antiviral treatment against HIV (highly active antiviral therapy [HAART]) and HCV (combined therapy with α-interferon , , .