Depression and Suicidality in Patients with Huntington’s Disease: VMAT2 inhibitors, including INGREZZA and INGREZZA SPRINKLE, can increase the risk of depression and suicidal thoughts and behavior (suicidality) in patients with Huntington’s disease. Balance the risks of depression and suicidality with the clinical need for treatment of chorea. Closely monitor patients for the emergence or worsening of depression, suicidal ideation, or unusual changes in behavior. Inform patients, their caregivers, and families of the risk of depression and suicidal ideation and behavior and instruct them to report behaviors of concern promptly to the treating physician. Exercise caution when treating patients with a history of depression or prior suicide attempts or ideation, which are increased in frequency in patients with Huntington’s disease., Find the dosing options for once-daily INGREZZA treatment for tardive dyskinesia and Huntington’s disease chorea. See Prescribing Info, including Boxed Warning., Ingrezza (valbenazine) is used to treat tardive dyskinesia (TD) and chorea associated with Huntington's disease. Ingrezza uses, side effects, doses, and more..