“We are thrilled to offer the first and only ready-to-use autoinjector for patients suffering from acute and cluster headaches,” said Joe Renda, Senior Vice President, Chief Commercial Officer, Specialty, Amneal. “Physicians are familiar with [dihydroergotamine], which is an effective and well-established therapy that provides sustained relief for . Our single-dose autoinjector represents an innovative therapeutic option for patients that allows for quick self-administration of the medication during these painful attacks without visiting the emergency room.”, BRIDGEWATER, N.J., May 15, 2025 -- Amneal Pharmaceuticals, Inc. (Nasdaq: AMRX) (“Amneal” or the “Company”) today announced that the U.S. Food and Drug Administration (FDA) has approved Brekiya (dihydroergotamine mesylate) injection, the first and only dihydroergotamine (DHE) autoinjector for the acute treatment of migraine with or , DHE can be used at any point during a migraine attack, and may protect patients from headache recurrence. 1, 3,4 Approximately 39 million Americans are living with migraine 7, and up to one .