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постановления министерства юстиции 19 от 21.01.2014, Immunoglobulin Test: High vs Low vs Normal Levels of (Ig) Antibodies, What Does It Mean If Your Immunoglobulin A Is High? | Immune Insights, Causes of High IgA Levels - SelfDecode Labs, IgA (summary and causes of reduced and increased levels), Elevated IgA - American Academy of Allergy, Asthma & Immunology, What is the significance of elevated Immunoglobulin A (IgA) levels?, IgA Blood Test Results Fully Explained - HRF - HRF - Health and Medical .
Conditions Back ConditionsDrugs & Supplements Back Drugs & SupplementsWell-Being Back Well-BeingMore Back More Privacy & More Subscribe Log In Search Subscribe What Is an Immunoglobulin Test?Written by Medically Reviewed by Jennifer Robinson, MD on September 19, 20234 min readThis test checks the amount of certain called immunoglobulins in your body.Antibodies are that your immune cells make to fight off bacteria, viruses, and other harmful invaders. The immunoglobulin test can show whether there's a problem with your .Some conditions cause your body to make too many or too few immunoglobulins.Having too few immunoglobulins in your gives you a greater chance of getting infections. Having too many could mean you have or an overactive .Types of ImmunoglobulinYour body makes a few different types of immunoglobulin antibodies, including these:Immunoglobulin A: IgA antibodies are found in the mucous membranes of the , , , and . They're also in fluids these membranes produce, like and tears, as well as in the .Immunoglobulin G: IgG is the most common type of antibody in your blood and other body fluids. These antibodies protect you against infection by "remembering" which germs you've been exposed to before. If those germs come back, your knows to attack them. Your doctor can test for IgG to figure out whether you've been infected by certain kinds of bacteria or viruses.Immunoglobulin M: Your body makes IgM antibodies when you are first infected with new bacteria or other germs.They are your body's first line of defense against infections. When your body senses an invader, your IgM level will rise for a short time. It will then begin to drop as your IgG level kicks in and increases to protect you long-term.Immunoglobulin E: Your body makes IgE antibodies when it overreacts to substances that aren't harmful, such as pollen or pet dander. Your doctor will likely measure your IgE levels if you have a blood test to check for .Why You Might Need This TestYour doctor might order an immunoglobulin test if you get a lot of infections -- especially infections of the , , , or .They may also order the test if you have: that doesn't go awayUnexplained weight loss that can't be explained by another causeSickness after traveling/ or (a type of ), or another condition that needs to be monitoredHow the Test is DoneDoctors often measure IgA, IgG, and IgM together to get a snapshot of your immune function. A lab tech will usually take a sample of your blood by inserting a needle into a vein in your arm. The blood collects in a tube or vial.Another way to do this test is with a sample of what’s called cerebrospinal fluid (CSF).CSF surrounds your and spinal cord. The doctor will take a sample of this fluid with a lumbar puncture (often called a “spinal tap”).For this, you go to an outpatient facility or a hospital. A technician will give you a shot in your back to help numb any .You will likely lie on your side with your knees pulled up to your chest, or you sit on a table. The technician inserts a hollow needle between two vertebrae in your lower and removes a small amount of fluid so it can be tested.What Do My Results Mean?The sample will be sent to a lab for testing. This might take a few days.Depending on your results, the doctor might need to do other tests, such as a:Complete blood count () blood test to check for kidney problemsIf your immunoglobulin level is high, it might be caused by:AllergiesChronic infectionsAn autoimmune disorder that makes your immune system overreact, such as , , or disease, such as multiple myeloma, , or Low levels of immunoglobulins mean your immune system isn't working as well as it should. This can be caused by:Medicines that weaken your immune system, such as or failureA weakened immune system that you were born with or developed (as with HIV/AIDS)Just because your immunoglobulin level is high or low doesn't mean you have one of these conditions.Each person's test can differ based on the method the lab uses to check the results. Talk to your doctor about your test results, and find out what you should do next.SourcesUpdate HistorySharePrintSOURCES:American Association for Clinical Chemistry: "Quantitative Immunoglobulins: At a Glance," "Quantitative Immunoglobulins: Test Sample," "Quantitative Immunoglobulins: The Test."Mayo Clinic: "Lumbar puncture (spinal tap): What you can expect."Nemours Foundation: "Blood Test: Immunoglobulins (IgA, IgG, IgM)."Pagana, Kathleen Deska. Mosby's Diagnostic and Laboratory Test Reference, 2016.University of Rochester Medical Center: "Quantitative Immunoglobulins."SharePrintMore on Health A-Z Recommended FEATURED Top doctors in , Find more top doctors on Search Related LinksPoliciesAboutFor Advertisers © 2005 - 2025 WebMD LLC, an company. All rights reserved. WebMD does not provide medical advice, diagnosis or treatment. , Just because your immunoglobulin level is high or low doesn't mean you have one of these conditions. Each person's test can differ based on the method the lab uses to check the results., Symptoms associated with high IgA levels often stem from underlying conditions. Common signs include frequent infections, chronic fatigue, joint pain, skin rashes, and abdominal discomfort. Recognizing these symptoms can assist in timely diagnosis and management of potential health issues..
High IgA can indicate chronic inflammation or an infection. Most labs consider values above 400 mg/dL in adults high. The upper limit varies by age and is lower in children and adolescents., High IgA (>4g/L) elevated IgA levels are nonspecific, but can be seen in pulmonary and gastrointestinal inflammatory diseases, some autoimmune conditions, liver disease, and plasma cell disorders; Low IgA (<0.8g/L) partial or complete IgA deficiency affects up to 1% of the population, and is commonly asymptomatic., Healthy 38 year-old female with isolated elevation of serum IgA 365mg/dl (47-320). IgM and IgG in normal range. Serum protein electrophoresis normal without M-protein detected., High serum IgA levels in patients with IgG4-related disease are associated with mild inflammation, sufficient disease-specific features, and favorable responses to treatments 7. Galactose-deficient IgA1 levels are elevated and heritable in African American patients with IgA nephropathy, indicating a risk factor for the disease 8 ., Blood test results for IgA are typically communicated as being either high, low, or normal. If there are high results, then this typically indicates the presence of an infection, an autoimmune disorder, chronic inflammation, or cirrhosis of the liver., Immunoglobulin A, or IgA, is a protein that can be found in the body, mainly in the mucous membranes. Its main function is to protect the body against infections. Learn more what IgA is for, what normal IgA levels are, and what high IgA or low IgA levels mean.