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составьте таблицу три склонения имен существительных, FDA Approves Tislelizumab Plus Chemo for PD-L1+ Unresectable , FDA Approves Tislelizumab/Chemo in Gastric/GEJ Adenocarcinoma, TEVIMBRA Approved in U.S. for First-line Treatment of Gastric , ESCC and GC/GEJC Treatment | TEVIMBRA® (tislelizumab-jsgr), FDA Approves Tislelizumab-jsgr (Tevimbra) Combo for Gastric , FDA Approves Tevimbra Combination for Gastric or , FDA Approves Tislelizumab-jsgr as First-Line Therapy for HER2 .
TEVIMBRA is a medicine that may treat certain cancers by working with your immune system. TEVIMBRA can cause your immune system to attack normal organs and tissues in any area of your body and can affect the way they work. These problems can sometimes become severe or life-threatening and can lead to death. You can have more than one of these problems at the same time. These problems may happen anytime during treatment or even after your treatment has ended., Key Takeaways Tislelizumab-jsgr (Tevimbra) approved for first-line treatment of HER2-negative gastric or GEJ adenocarcinoma with PD-L1 expression. Phase 3 RATIONALE-305 trial showed significant , The FDA previously accepted a biologics license application BLA for tislelizumab plus chemotherapy to treat patients with locally advanced or metastatic gastric or GEJ adenocarcinoma in February 2024. 4 References TEVIMBRA approved in U.S. for first-line treatment of gastric and gastroesophageal junction cancers in combination with chemotherapy..
The additional indication for first-line G/GEJ cancers is based on results from BeiGene’s RATIONALE-305 (NCT03777657), a randomized, double-blind, placebo-controlled, global Phase 3 trial to evaluate the efficacy and safety of TEVIMBRA in combination with chemotherapy as a first-line treatment for adult patients with advanced unresectable or metastatic G/GEJ cancer. The study met its primary , TEVIMBRA is a prescription medicine used to treat adults with: cancer of the tube that connects your throat to your stomach (esophageal cancer). TEVIMBRA may be used in combination with chemotherapy that contains platinum as your first treatment when your esophageal cancer: is a type called squamous cell carcinoma, and cannot be removed with surgery or has spread to other parts of the body , The U.S. Food and Drug Administration approved tislelizumab-jsgr (Tevimbra) in combination with chemotherapy as a first-line treatment for adults with unresectable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinomas whose tumors express PD-L1., A drug called Tevimbra (tislelizumab-jsgr) has been approved for use with chemotherapy as first-line treatment of PD-L1 positive unresectable or metastatic HER2-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma. Tevimbra was approved earlier in 2024 to treat unresectable or metastatic esophageal squamous cell carcinoma., The FDA approved tislelizumab-jsgr (Tevimbra) in combination with platinum and fluoropyrimidine-based chemotherapy as a first-line treatment for unresectable or metastatic HER2-negative (HER , Michael K. Gibson, MD, PhD, FACP, discusses the historical management of gastric cancer and introduces a treatment option for gastric or gastroesophageal junction adenocarcinoma..