Treatment for Crohn’s disease includes medicines that reduce inflammation and calm your immune response. Studies suggest that treating the inflammation likely improves the long-term outcomes of Crohn’s disease. You may also need treatments to manage specific symptoms, like pain and diarrhea., Aminosalicylates are thought to be effective in treating mild-to-moderate episodes of Crohn’s disease and useful as a maintenance treatment in preventing relapses of the disease. They work best in the colon and are not particularly effective if the disease is limited to the small intestine. Examples: Sulfasalazine. Mesalamine. Olsalazine , Crohn's Disease Treatment: Surgery. About 40 to 60 percent of patients with ileal Crohn's disease (Crohn's disease in a certain part of your small intestine) need surgery during the first 10 years of symptoms. If you develop an abscess or perforation, you may need surgery earlier., The disease and its treatments also may increase your risk of certain cancers, including colorectal cancer. That’s why routine screenings and ongoing medical care are essential. Risk factors for Crohn’s disease. You can develop Crohn’s disease at any age, but it’s most often diagnosed between the ages of 20 and 29., Medication is the main treatment for Crohn's disease, but many people use complementary therapies to help ease symptoms. They include: Mind-body therapies such as relaxation, meditation, hypnosis , Crohn's disease (CD) is an idiopathic inflammatory disorder of unknown etiology with genetic, immunologic, and environmental influences. The incidence of CD has steadily increased over the past several decades. The diagnosis and treatment of patients with CD has evolved since the last practice guideline was published..