Sutimlimab, sold under the brand name Enjaymo, is a monoclonal antibody that is used to treat adults with cold agglutinin disease (CAD). [1] [3] [4] It is given by intravenous infusion. [1]Sutimlimab prevents complement-enhanced activation of autoimmune human B cells in vitro. [5]The most common side effects include headache, high blood pressure, urinary tract infection (infection of the , ENJAYMO (sutimlimab-jome) is indicated for the treatment of hemolysis in adults with cold agglutinin disease (CAD). 2 DOSAGE AND ADMINISTRATION 2.1 Recommended Vaccinations . Vaccinate patients against encapsulated bacteria at least 2 weeks prior to initiation of ENJAYMO therapy according to the most current Advisory Committee on Immunization, ENJAYMO HCP Indication and Important Safety Information INDICATION. ENJAYMO ® (sutimlimab-jome) is indicated for the treatment of hemolysis in adults with cold agglutinin disease (CAD).. IMPORTANT SAFETY INFORMATION . CONTRAINDICATIONS. ENJAYMO is contraindicated in patients with known hypersensitivity to sutimlimab-jome or any of the inactive ingredients., Enjaymo is a medicine for treating haemolytic anaemia (excess breakdown of red blood cells) in adults with cold agglutinin disease (CAD). CAD is a rare blood disorder where the immune system (the body’s natural defence) recognises red blood cells as foreign and attacks them. This causes agglutination (clumping together) and haemolysis , ENJAYMO intravenously weekly for the first two weeks, with administration every two weeks thereafter.Administer ENJAYMO at the recommended dosage regimen time points, or within two days of these time points. If a dose is missed, administer as soon as possible; thereafter, resume dosing every two weeks., ENJAYMO is a medicine that affects your immune system. ENJAYMO may lower the ability of your immune system to fight infections. ENJAYMO increases your chance of getting serious infections including those caused by encapsulated bacteria, including Neisseria meningitidis, Streptococcus pneumoniae, and Haemophilus influenzae type B. These serious .