Oral steroids are popularly used to treat nasal polyps, but topical medications and steroid injections are other options that can help you avoid surgery., Treatment Chronic sinusitis, with or without polyps, is hard to clear up. Treatment depends on the cause of the swelling and irritation. The goal is to lessen symptoms and improve life. Medicines Treatments might include: Nasal steroids. These nasal sprays include fluticasone (Flonase Allergy Relief, Xhance), budesonide (Rhinocort), mometasone (Nasonex 24hr Allergy), triamcinolone (Nasacort , Topical steroids: This is usually the first treatment doctors recommend for nasal polyps. These medications, delivered into your nasal passages via drops, sprays, nebulizers, and inhalers, reduce , with nasal polyps will also have asthma. Polyps are usually bilateral, be wary of patients presenting with unilateral symptoms or a unilateral polyp, as this may hera Corticosteroids remain the mainstay of treatment for this condition; care should be taken when the patient is on other corticosteroids to avoid adrenal insufficiency., The time-tested medical treatment for obstructing nasal polyps is oral corticosteroids. This nonspecific anti-inflammatory agent significantly reduces the size of the inflammatory polyps and improves symptoms quickly. Unfortunately, the effects are short lasting, and polyps frequently regrow and cause similar symptoms within weeks to months., The study team found 61 studies of topical steroids that used a randomized controlled design to test how well the medicine works in people with chronic rhinosinusitis and nasal polyps. There were 8 different types of topical steroids that were grouped together in the analysis..