Overview of Ankylosing SpondylitisAnkylosing spondylitis is a type of arthritis that causes inflammation in the joints and ligaments of the spine. It may also affect peripheral joints like the knees, ankles, and hips. Normally, the joints and ligaments in the spine help us move and bend. If you have ankylosing spondylitis, the inflammation in the joints and tissues of the spine can cause stiffness. In severe cases, this may cause the vertebrae (bones in the spine) to fuse (grow together). When the vertebrae fuse, it can lead to a rigid and inflexible spine. (For more information about the anatomy of the spine, see our .)Many people with ankylosing spondylitis have mild episodes of back pain and stiffness that come and go. But others have severe, ongoing pain with loss of flexibility in the spine. In addition, other symptoms may develop depending on which other areas of the body are affected by the disease. Some people with ankylosing spondylitis develop eye disease (uveitis), skin disease (psoriasis), or gut disease (inflammatory bowel disease).There is no cure for ankylosing spondylitis but there are many treatment options to help control symptoms. Recommended therapies may include exercise, physical and/or occupational therapy to improve mobility and posture, and medications to help manage pain, control inflammation, improve posture and body position, and slow the progression of the disease. With treatment, most people with ankylosing spondylitis can have productive lives., Ankylosing spondylitis, also known as axial spondyloarthritis, is an inflammatory disease that, over time, can cause some of the bones in the spine, called vertebrae, to fuse. This fusing makes the spine less flexible and can result in a hunched posture. If ribs are affected, it can be difficult to breathe deeply., Ankylosing spondylitis is a rare type of arthritis in your spine that most often affects people younger than 45. Learn more about symptoms, causes, risk factors, diagnosis, treatments, home .