Lymphoma stage: DLBCL is staged from I (localized) to IV (advanced). Early-stage lymphoma, where the cancer is confined to one or two areas, has a better prognosis. In stage IV lymphoma, the cancer has spread to distant organs like the liver or bone marrow, which makes treatment more challenging., Stage IV lymphoma has spread outside your lymph nodes to many places in your body. NHL tends to spread to the bone marrow, liver, lungs, and the fluid around the brain. Sometimes doctors, As with many cancers, there are four stages of lymphoma. Stage 4 lymphoma is often treatable. A person’s prognosis depends on many factors, which include the type of lymphoma and the, In understanding stage 4 lymphoma prognosis, it is essential to appreciate not just the survival rates, but also the treatment options available, and how these elements impact the quality of life for patients. Analyzing recent research provides deeper insights into advancements in treatment modalities and how they shape the landscape of care., Stage 1 Non-Hodgkin's Lymphoma survival rate: Early-stage (I), localized disease: 81.1%; Stage 1 and Stage 2 Non-Hodgkin's Lymphoma survival rate: Early-stage (I, II), regional disease: 70.5%; Stage 3 and Stage 4 Non-Hodgkin's Lymphoma survival rate: Later-stage (III, IV), metastasized disease: 58.5%, Prognosis for stage 4 lymphoma also depends on the cancer type — along with patient age, overall health, and response to treatment. There are two main categories of lymphoma: Both.