понос у ребенка 1 года без температуры чем лечить
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понос у ребенка 1 года без температуры чем лечить, Chronic rhinosinusitis in cystic fibrosis: a review of therapeutic , Chronic Rhinosinusitis with Nasal Polyposis in People with Cystic Fibrosis, Nasal Polyps in Cystic Fibrosis Patients: Causes, Symptoms, and , Nasal Polyps in Cystic Fibrosis - CHEST, Treatment and Prognosis of Nasal Polyps in Cystic Fibrosis, Why Do Cystic Fibrosis Patients Get Nasal Polyps?, Nasal polyposis in cystic fibrosis: follow-up of children and .
Davidson et al. reported that 20 mg of tobramycin added to the last 50 mL of nasal saline irrigation once a day after sinonasal surgery decreased the rate of recurrent exacerbations in children and adults with CF []. Prolonged aeration of the sinuses was observed in sinus MRI scans in CF patients after sinonasal irrigation with saline and antibiotics. Additionally, nebulizations with tobramycin and colistin were able to prevent the colonization of paranasal sinuses mucosa by bacteria []. Nevertheless, studies showed that the standard ways of nebulization did not reach the expected drug concentration in sinuses, as their natural openings were obstructed secondary to CRS []. In contrast to standard nebulization, promising results were found for the sinonasal drug delivery using PARI SINUS™ nebulizer []. PARI SINUS™ nebulizer is a novel tool, which generates pulses of aerosol that are subsequently delivered to paranasal sinuses []. RCT conducted by Mainz et al. revealed that tobramycin (80 mg/2 mL) delivered by PARI SINUS™ to paranasal sinuses once a day for over 28 days led to a significant reduction of P. aeruginosa colonies in the majority of CF patients []. A significant decrease in SNOT-20 scores was also observed in the studied cohort []. Currently, there is also ongoing multi-center double-blind RCT investigating the influence of nasally nebulized tobramycin on sinonasal symptoms, endoscopic scores, QOL, and pulmonary function in CF-related CRS []., Chronic rhinosinusitis (CRS) is observed in almost 100% of patients with cystic fibrosis (CF). CF-related CRS treatment is extremely challenging because of the underlying genetic defect leading to its development., Management of Nasal Polyps in People with Cystic Fibrosis Until recently, treatments for PwCF were primarily focused on treating the end-organ manifestations of CF [46]..
Understanding the relationship between CF and nasal polyps is essential for early detection and effective management. This article delves into the causes, symptoms, diagnosis, and treatment options for nasal polyps in cystic fibrosis patients, offering valuable insights for patients, caregivers, and healthcare providers., Study objectives: Nasal polyps frequently appear in patients with cystic fibrosis (CF). The aims of this study were to focus on what problems (symptoms, endoscopic findings, and laboratory correlates) nasal polyps cause the CF patient, and how these correlate to the total health situation of this patient group., Polyposis was the initial symptom of cystic fibrosis in 13 patients. Common symptoms included obstruction to nasal air flow, mouth breathing, epistaxis, and rhinorrhea. Intranasal and oral corticosteroids and antihistamines were ineffective in preventing recurrences but did occasionally afford symptomatic relief of obstruction., While nasal polyps can occur in children, they are often associated with conditions like chronic sinusitis, allergic rhinitis, or cystic fibrosis. If left untreated, polyps may continue to grow and obstruct the nasal passages, thus requiring medical intervention., Objective To assess the incidence of nasal polyposis, the response to medical treatment, recurrence and the need for surgical intervention in children and adolescents with cystic fibrosis during a three-year follow-up., Cystic fibrosis (CF) is a life‐shortening, autosomal recessive disease that leads to abnormal electrolyte concentration in exocrine secretions. Secretion stasis in paranasal sinuses determines chronic rhinosinusitis (CRS) and nasal polyposis. Endoscopic sinus surgery is used to open the sinuses and allow medical treatment to work properly..