Koāte ® (antihemophilic factor [human]), also known as Koāte-DVI, is a human plasma-derived FVIII indicated for the treatment and prevention of bleeding episodes in patients with hemophilia A. Initially approved in the US in 1974, the processing methods have been updated over the years to make the product safer from viral contamination., Jivi (Antihemophilic Factor [Recombinant] Pegylated-Aucl) Overview Jivi is a recombinant antihemophilic factor approved by the U.S. Food and Drug Administration (FDA) for the treatment and management of hemophilia A (congenital factor VIII [8] deficiency) in previously treated… read more, Recombinant antihemophilic factor, porcine sequence. Historically, porcine factor VIII has provided a good effect. A porcine sequence recombinant FVIII (rpFVIII; Obizur) was approved by the US Food and Drug Administration (FDA) in 2014 for treatment of bleeding episodes in adults with acquired hemophilia., , , .