Spiriva Respimat Solution for Inhalation is a clear, colourless solution of tiotropium bromide monohydrate filled into a 4.5ml cartridge. Each cartridge providing 60 puffs (30 medicinal doses)., HIGHLIGHTS OF PRESCRIBING INFORMATION These highlights do not include all the information needed to use SPIRIVA RESPIMAT safely and effectively., SPIRIVA RESPIMAT (tiotropium bromide monohydrate) is indicated as a long-term once-daily maintenance bronchodilator treatment of airflow obstruction in patients with chronic obstructive pulmonary disease (COPD), including chronic bronchitis and/or emphysema, and for the reduction of exacerbations., The drug product, SPIRIVA RESPIMAT, is composed of a sterile, aqueous solution of tiotropium bromide filled into a 4.5 mL plastic container crimped into an aluminum cylinder (SPIRIVA RESPIMAT cartridge) for use with the SPIRIVA RESPIMAT inhaler., Learn more about the safety profile, side effects and dosing of SPIRIVA RESPIMAT (tiotropium bromide) 2.5 mcg inhalation spray. See ISI, PI & Med Guide., Insert cartridge before use. Discard 3 months after insertion of the cartridge into inhaler. *Each actuation delivers 2.5 mcg of tiotropium (equivalent to 3.124 mcg of tiotropium bromide.