The number of treatment options for prostate cancer has exploded over the last decade. That trend is showing no signs of letting up, with the Food and Drug Administration’s (FDA) recent decision to expand the approved uses of enzalutamide (Xtandi) to treat people with prostate cancer that hasn’t spread, or metastasized, to other parts of the body., Xtandi is used to treat certain types of prostate cancer. Common side effects include hot flashes, constipation, diarrhea, and muscle or joint pain. Xtandi needs to be swallowed whole. Talk to , Xtandi is a brand-name prescription drug that's used to treat certain types of prostate cancer. Learn about side effects, warnings, dosage, and more., Chemotherapy is a class of medication that targets and kills cancer cells in your body. Xtandi (enzalutamide) doesn’t kill cancer cells. Instead, it’s a form of hormonal therapy called an androgen receptor inhibitor or antiandrogen. It works by blocking the male sex hormone, testosterone, in your body., On November 16, 2023, the Food and Drug Administration approved enzalutamide (Xtandi, Astellas Pharma US, Inc.) for non-metastatic castration-sensitive prostate cancer (nmCSPC) with biochemical , Enzalutamide (MDV3100, XTANDI (®)) is an androgen receptor inhibitor that is indicated for the treatment of metastatic, castration-resistant, prostate cancer (mCRPC) that has progressed despite treatment with docetaxel. This article reviews the pharmacology, efficacy and tolerability of enzalutamide relevant to this indication. In a randomized, double-blind, placebo-controlled, multinational .