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AboutLog inJoinSkipping Strattera on weekends - CHADD's Adult ADH...CHADD's Adult ADHD Support26,558 members•6,514 postsJoinPostPostHomeAboutPostsMembersSkipping Strattera on weekendspollinator•2 months ago•10 RepliesI have mild-moderate ADHD inattentive type. I also have issues with anxiety and took Lexapro for over a decade to treat that. I didn't think I could take medication for ADHD because of the anxiety and controlled high blood pressure.In December of 2023 my therapist suggested that I was on the wrong medication. I should take Strattera and not Lexapro it will help with the anxiety and the ADHD. I started with 40mg and slowly increase to 80mg over time. I did not like it, I was irritable and angry, although very productive at work and not anxious. So I started decreasing my dose and over months I have ended up back at 40 mg and skipping it on the weekends.I'm less angry and it's still helping with the executive disfunction and anxiety. However, I've noticed mood swings and I thought it may be because I shouldn't be skipping days, if I don't skip days the angry comes back. I know what the literature says but I'm curious if anyone takes it like this and what their experience has been.Thank you for any advice you provide.Written bypollinatorTo view profiles and participate in discussions please join or log in.Read more about...StratteraLexaproReply Like (0)Save postReport10 Repliesoldest•newestSelf_Health2 months agoI tried strattera but it made me feel like I was treading into dark feelings and I personally couldn't continue.Reply (0)ReportCinnah2 months agoHi. I started Strattera Jan 2025 at 40mg. In March, increased to 80 mg. Honestly, it feels like I’m taking a vitamin. I do take bupropion 300mg in the morning. And Paxil at night. I’ll be looking for a change in adhd meds next appt. Good luck!Reply (0)ReportMmagusin2 months agois it possible the irritability was from stopping the Lexapro? Reply (0)Reportpollinator• in reply toMmagusin2 months agoYes, but it didn't get bad until over 6-months after stopping the Lexapro. My doctor said you cannot take Lexapro and Straterra together and the Lexapro causes me to gain weight and feel blah, so I don't miss it.Reply (0)ReportSTEM_Dad• in reply topollinator2 months agoThe two medications can have a negative interaction.Lexapro is an SSRI (selective serotonin reuptake inhibitor). Strattera is primarily an SNRI (selective norepinephrine reuptake inhibitor), but has been found in some studies to also act like a mild SSRI.The potential interaction between the two includes the danger of Serotonin Syndrome, just as too high a dosage of an SSRI could.I was prescribed a low dosage of Lexapro for situational depression while taking 40mg of Strattera (which is typically the low dosage for adults), and my doctor warned me of the potential interaction. He told me the warning signs to watch out for, and to go to the hospital if I experienced them. I didn't experience it, but I was on the lowest dosage of both medications. (After a few months on Lexapro, I was able to discontinue it. Remembering the weirdness from my first time on Lexapro and weaning off too quickly, I weaned off over about 6 weeks, as I had discussed with my doctor when I started on it the second time.)Reply (0)ReportDancePranceTrance2 months agoLow dose Strattera (generic atomoxetine) does nothing for my focus. I've taken it for years at 100 mg. The only side effects I've experienced are a slight blunting of appetite and I must take it on a full stomach and before 10 am. Empty stomach, then I get very, very queasy. Take it after 10 am, then I find it difficult or impossible to go to sleep at bedtime. I don't intentionally skip doses but occasionally forget. Oh the irony of having to remember a drug for distractibility and time blindness when the world is so full of lovely distractions and clocks are so easy to ignore. Reply (1)Reportanotheradhdhead2 months agoI can't skip, and even trying a different dose makes me incredibly emotional for the next 12-24hrs or so. Reply (1)ReportSTEM_Dad2 months agoFor Strattera, 40mg is usually the lowest dosage for adults.Most people on it get increased to 60, 80, or 100mg (with 120mg being the maximum dosage).My ADHD was well treated on atomoxetine (generic Strattera) for the 3 years that I was on it. Most of that time, I was on 40mg, and for 6 months at 60mg (which had minimal improvement and more noticeable side effects for me).Atomoxetine is supposed to be taken every day, because it has to first build up in the body to reach a therapeutic level, then that level has to be maintained. Taking two days off it in a row might be causing enough of a dip to affect how you feel. (It you went off it completely, without weaning, it would almost certainly cause very unpleasant effects.)• The plus side is that it keeps working 24 hours a day. The minus side is that if you experience any side effects, then those can also affect you any time of day. (Some people do metabolize atomoxetine differently, and might feel the effects more over the first half of the day after taking, and a draw down effect for the second half of the day. I only know this based on what others have said on forums like this, because it's not my experience and I haven't seen anything written in the published studies about this daily variance.)~~~Since Strattera is also used to treat children with ADHD, it is also manufactured in lower dosages (in 5mg, 10mg, and 25mg capsules).You should talk to your doctor about adjusting your dosage down from 40mg. Perhaps your dosage can be reduced to 25mg, 30mg (25+5 or 10+10+10), or 35mg (25+10). Then, you could take it daily without the side effects that you were getting on taking 40mg every day. ~~~Some people even have a secondary medication to help with treating their ADHD: guanfacine.Guanfacine is actually a type of blood pressure medication which has been found to help with treating ADHD, not usually as a primary medication, but as an added medication. According to Dr. William Dodson and other ADHD experts, guanfacine helps with the emotional disregulation which often comes with ADHD.So, you might ask your doctor about it do see if they think it might help you.~~~~~After 3 years on atomoxetine, I switched to bupropion (generic Wellbutrin), which I feel helps me a bit more.Atomoxetine acts only on norepinephrine. Bupropion acts on both norepinephrine and dopamine.Reply (1)Reportpollinator• in reply toSTEM_Dad2 months agoVery interesting, I will talk to my doctor about the lower dose and the guanfacine. Thank you! Reply (0)ReportNotAChevy2 months agoim also on Strattera (40mg), but haven't encountered anything like that. I take it 7 days a week and it's been super helpful. Maybe your psychiatrist can help with this?? Reply (1)ReportNot what you're looking for?You may also like...Bad reaction to VyvanseMy 16 year old daughter has recently been diagnosed with severe ADHD, without hyperactivity...kevans319•7 years ago13 RepliesChanging meds: Strattera to Wellbutrin TL;DR - I asked my doctor to do a trial of treatment with bupropion (Wellbutrin). I'm hoping that...STEM_Dad•1 year ago9 RepliesAdding an Antidepressant to ADHD and Anxiety MedsMy psychiatrist constantly suggests adding Lexapro to all of my other medications (vyvanse,...Halem1982•7 years ago32 RepliesExperiences with Strattera?Hi everyone,, Detailed dosage guidelines and administration information for Strattera (atomoxetine hydrochloride). Includes dose adjustments, warnings and precautions., To begin your Strattera treatment, your doctor will prescribe you a low dose. After 3 days, they’ll likely increase your dose to a maintenance (long-term) dose..
The typical Strattera dosage for adults is 40 mg by mouth once daily, which can be increased to a target dosage of 80 mg after a few days. For children ages 6 to 17, their dose typically starts at 0.5 mg per kg body weight per day if they weigh 154 lbs (70 kg) or less., The typical dosage for Strattera ranges from 10mg to 100mg. Providers will select a dose for patients determined by diagnosis, age, weight, medical history, how well the first doses work, and how well the medication is tolerated., Medscape - Attention deficit hyperactivity disorder (ADHD)-specific dosing for Strattera (atomoxetine), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy, In adults, start with 40 mg QAM, and increase to 40 mg BID or 80 mg QAM after 3-7 days. Maximum recommended dose is 100 mg/day or 1.4 mg/kg, whichever is lower. Studies have shown that once daily dosing is as effective as BID dosing, but BID dosing is better tolerated in terms of GI side effects., I was prescribed a low dosage of Lexapro for situational depression while taking 40mg of Strattera (which is typically the low dosage for adults), and my doctor warned me of the potential interaction. He told me the warning signs to watch out for, and to go to the hospital if I experienced them., Strattera is taken orally, with or without food, once or twice daily. The most common reason why patients don’t experience optimal benefits from Strattera is a high level of side effects, which prevents them from taking a dose high enough to be therapeutic..